11:52 AM PT -- James Rosemond Jr., Ice Spice's manager, says he spoke to Cleotrapa's manager after her posts went viral ... they both agree Cleo handled the situation poorly, especially since she doesn't understand industry politics!!!

Ice Spice has lost yet another BFF, who's claiming to being used as a loop in her BB Belt -- and her enemies just might be teaming up!!!

Rapper Cleotrapa used her Labor Day Weekend to completely unload on Ice Spice ... dropping a 45-minute TikTok video where she accused the "Munch" rapper of being a fake friend ... and claiming she experienced less-than-VIP treatment as the opening act on Ice's Y2K Tour.

According to Cleo, she had to foot the bill for her own hotels and meal per diem ... and was forced to use stinky bathrooms as her dressing rooms.

Cleo says she wasn't paid for her time -- which she had no problem with -- but the final straw was realizing Ice never had any intention to expose Cleo to her Munchkin fanbase -- but rather used her as a prop to look like the better performer.

Ice hosted an X Space to defend herself against Cleo ... and basically chalked it up to jealousy. Ice experienced a very public breakup with singer Baby Storme earlier this year -- who didn't miss the opportunity to pile onto the explosion!!!

Storme released a ton of text messages of Ice ragging on Nicki Minaj, and clashed with Cleo at the time ... but came to an accord that their common enemy is the Notorious I.C.E!!!

We reached out to Ice's camp to see if they'll be responding -- in the form of a diss song. It's totally the year for rap beef!!!