Duke -- ranked eighth in the country -- just lost 83-79 in a nail-biter match against unranked Wake Forest, a huge upset that could have major conference championship implications.

As students of the winning side tend to do after a big win, hundreds of excited college kids rushed the court and they appear to have injured the projected top-10 overall pick.

From far away, it was unclear exactly what happened, though Kyle looked to be in considerable pain ... but ESPN had the overhead view of the incident, and it's painful to watch.

It seems one fan ran right into Kyle's leg, bending it the wrong way and apparently spraining his ankle -- all while talking trash to the basketball phenom instead of paying attention to where he was running.

Filipowski nearly collapses, doubled over by the collision before hobbling toward his teammates who supported his weight -- basically, dragging him to the locker room.

Obviously, Kyle's squad was incensed after the game with his coach Jon Scheyer openly questioning when the NCAA was going to ban courtstorming.

Kyle also opened up about the incident after the game ... and he says he thinks the fan hit him on purpose, trying to injure him.

A major injury right now could seriously affect Kyle's future livelihood BTW ... 'cause NBA.com just ranked him as the projected 9th overall pick in this year's draft -- meaning an astronomical payday.