A statement from Christine's family released reads, "She passed away peacefully at hospital this morning, Wednesday, November 30th 2022, following a short illness. She was in the company of her family. We kindly ask that you respect the family’s privacy at this extremely painful time, and we would like everyone to keep Christine in their hearts and remember the life of an incredible human being, and revered musician who was loved universally."

One of her bandmates, Stevie Nicks, expressed her pain after the loss of her "best friend in the whole world" ... saying she had no clue Christine was sick until this past weekend, and wanted to be with her, but was told to wait.

Stevie says the song "Hallelujah" by HAIM has been on her mind ever since she found out Christine was ill ... saying "I always knew I would need these words one day." She finishes her letter, "See you on the other side my love. Don't forget me."

Christine joined the group in 1970 -- they formed in 1967 -- and was inducted into the Rock and Roll Hall of Fame with Fleetwood Mac in 1998.

Christine also announced in 1998 she was leaving the band -- citing a fear of flying and panic attacks as part of the reason she needed to stop. She was somewhat retired for several years before releasing a solo album.

Luckily for fans, Christine rejoined the band before the On with the Show tour in 2014.

The group released a statement shortly after the announcement of her death, "There are no words to describe our sadness at the passing of Christine McVie. She was truly one-of-a-kind, special and talented beyond measure. She was the best musician anyone could have in their band and the best friend anyone could have in their life. We were so lucky to have a life with her. Individually and together, we cherished Christine deeply and are thankful for the amazing memories we have. She will be so very missed."

We talked to Christine in 2019 in NYC about the future of the band and if they'd ever get back together.

Christine was 79.