The Arizona Cardinals receiver -- one of the best in the NFL -- is making his return to the field after serving a 6-game suspension for PEDs ... and he's amped!

The 30-year-old even dropped a hype video celebrating his comeback hours before the Cardinals' "Thursday Night Football" home game against the New Orleans Saints.

"Don't call it a comeback," DHop captioned the clip.

The video shows the 5-time Pro Bowler's recent workout with a mix of LL Cool J's "Mama Said Knock You Out' song and Black Sheep's "The Choice Is Yours".

Several NFL players showed support for Hopkins in the comments ... including teammate Budda Baker who wrote, "It’s Time!!! 🔥🔥🔥"

As we previously reported, DH was suspended in May for violating the league's PED policy. Hopkins initially appealed the punishment, before withdrawing.

His return couldn't come at a better time ... the Cardinals just lost star receiver Marquise "Hollywood" Brown for a month due to a foot injury.

And, Hopkins is one of Kyler Murray's favorite targets ... in the last two regular seasons, the two connected for 1,979 yards and 14 touchdowns.

"I'm excited to have him back," the Cardinals QB said earlier this week, "He's been waiting on this moment. He's an electric player."

The Cardinals are currently last in the NFC West but with DHop back ... AZ could make a run.