David Spade had nice things to say about Roseanne ... that is until our photog asked if he'd ever work with her again.
We got David Friday night in WeHo leaving Craig's, and at first he was chatty ... how he opened for Roseanne back in the day, when neither was making any real money.
He was also quick to say how funny she is, but then ... we ask him a question that's maybe a little too hot to handle ... which moves David's finger in the direction of the window switch.